Down syndrome. Homeopathic remedies. Kader Kochi.

Down syndrome is a genetic condition with mental subnormality in which a person has 47 chromosomes instead of the usual 46.This congenital disorder was first described by John Langdon Haydon Down (18 November 1828, 7 October 1896), an English physician in 1866. Down syndrome is not usually inherited from parents. The most cases of Down syndrome (95%) are usually caused by some changes during the development of the ovum, sperm cell, or embryo.

More than 75% of Down syndrome defects occur due to an extra chromosome 21 within the ovum. Less than 25% of cases occur due to an extra chromosome in the sperm cell. Some rare cases the ovum and sperm cells are normal. It also calls trisomy 21 (> 90%). It is also known as 'Up syndrome' because of the cheerful personality.

It occurs about once in every 600 - 800 births. Gender, race, and ethnicity do not appear to play a role in the development of the disorder. It affects an equal number of boys and girls.

RISK FACTORS

Mothers who are 35 years and older. As a woman's age increases, the risk of having a Down syndrome baby increases.

Woman who has child with Down syndrome.

Chemical Toxicity: Environmental chemical pollutants, Petrochemical pollutants, Bisphenol A in plastic, Heavy metal pollution, Alcohol, and Tobacco smoke toxin, Manganese toxicity etc. have some role.

CLINICAL FEATURES

The characteristic features of Down syndrome vary from person to person and can range from mild to severe.

 

Head	Separated joints between the bones of the skull. Small or abnormal shaped head. Flat area on back of head. Flat appearing face. Rounded cheeks. Small chin.
Eyes	Upward slanting eyes. Extra folds of skin located at the inside corner of eye. The inner corner of the eyes may be rounded instead of pointed. White spots on the colored part of the eye.
Ear	Small, low-set, misshapen ears.
Nose	Low-set, look forward. Flat bridge.  Small nose.
Mouth	Small and irregularly shaped. Narrow and high palate. Protruding of tongue.
Neck	Loose skin at the nape of the neck.
Trunk	Umbilical hernia. Short stature. Dysplastic pelvis.
Upper extremity	Small, wide hands with short fingers. An unusual deep crease across the center of the palm. Malformed fifth finger. Overly-flexible joints.
Lower extremity	Weak muscles. Wide space between the big and the second toes. Unusual creases on the soles of the feet. Overly-flexible joints. Short legs.
Mind	Behavioral characteristics  include calm, cheerfulness, gentleness, patience, tolerance and less responsive. Some are anxious and impulsive. Low intellectual ability. I.Q range varies in between 20-70.

 

Delayed physical, mental and social development.

Many different medical conditions are seen in people with Down syndrome

Congenital heart disease ( 30 - 50%).They include Atrial Septal Defects, Ventricular Septal Defects, Endocardial Cushion Defects or Tetralogy of Fallot. Severe heart problems may lead to early death. Malformations of the gastrointestinal tract (5-7%). They include esophageal atresia, or duodenal atresia.

Mental retardation.

Epilepsy.

Eye problems, poor vision, and early cataract.

Dentition delayed, irregular development of teeth and Crooked teeth.

Hypothyroidism.

Men with Down syndrome are commonly sterile. Women with Down syndrome are fertile. About 50 % of babies of these women will be born with Down syndrome. Some individuals with Down syndrome may live independently as adults, while others may require long-term care and support.

Possible complications

Early and massive vomiting due to esophageal atresia or duodenal atresia.

Sleep apnea due to narrowing of upper airway.

Recurrent upper respiratory infections.

Leukemia (30%). It can cause early death.

Hip joint dislocation.

Endocarditis.

Chronic constipation. 

Dental problems.

Deafness or balance complaints due to recurrent ear infections.

Cognitive disabilities, Dementia, and Alzheimer’s disease.

Premature senility.

Weakness at upper part of back.

Prognosis in Down syndrome depends on the severity of related health problems like heart defects, leukemia, and infectious diseases. Although many Down syndrome children have physical and mental limitations, they can live independent and productive lives well into adulthood. The average age at death for an individual with Down syndrome is about 50 to 55 years.

Preventive treatment

Genetic and psychological counseling for persons with a family history of Down syndrome who wish to have a baby.

Provide Calcium phosphate 3 x for boys and girls of family.

Prefer milk products than alcohol during honeymoon.

Avoid Ginger, Garlic and spicy foods during Honeymoon. 

Avoid excess of broiler chicken during Honeymoon celebration.

Avoid cattle feed contaminated with Fungicide, Arsenic and Ergot. 

Avoid much Alcohol, Cabbage and Mustard seeds and Onions in daily life.

Avoid shellfish and bottom fish as it contains heavy metals like Mercury and Lead.

Avoid food items with coloring agents, artificial sugar, Trans fat and acrylamide.

Avoid food items contaminated with Thallium and insecticide (during childhood).

Avoid pepper and cloves during pregnancy.

Protect from mosquito bite (day bite) during pregnancy (Zika virus infection).

Homeopathic treatment

A. Anti miasmatic remedies.

Calcarea carbonate(Pearls), Magnesium phos, Natrum mur.

Anti miasmatic remedies.

Allium sativa, Viscum album. 

Anti miasmatic remedies.

Veratrum album, Chelidonium, Thuja, Valariana.

B. Miasmatic remedies. 

Ricinus communis, Syzygium aromaticum, Calotropis,  Alfalfa, Cardamom, Olibanum, Manganum oxydatum nitricum.

Miasmatic remedies. 

Cinchona. 

Miasmatic remedies.

Arsenicum, Tabacum. Arsenic sulphide.

Supporting treatment                     

Low Immunity

Ocimum sanctum, Withania somnifera.

Anemia

Cardus marianus, Ginseng.

Anti-microbial medicines

Absinthium, Allium sativa, Berberis vulgaris, Echinacea, Eucalyptus, Ipecac, Hydrastis.

Dementia

Acorus calamus, Brahmi, Fenugreek, Ginkgo biloba, Hydrocotyle, Nux vomica, Physostigma, Conium maculatum, Ginseng, Rauwolfia, Salvia officinalis, Secale cor, Veratrum alb, Withania somnifera, Celastrus paniculata.

Insomnia

Passiflora, Valeriana, Withania somnifera.

Hypothyroidism

Fucus vesiculosus, Kali iodide.

Low muscles tone

Belladonna, Nux vomica, Calcium carbonate.

Some natural symptomatic remedies

Neurological deficit from   suppressed skin lesion	Sulphur, Azadirecta, Viscum album.
Weak muscles	Aconitum, Belladonna, Causticum,  Gelsemium, Kali carb, Natrum mur,  Plumbum met, Kali mur.
Alzheimer’s disease	Alumina, Argentum nitricum, Hyoscyamus,  Lobelia, Natrum mur, Silicea, Zinc met.
Weak nerve cells	Syzygium aromaticum, Arsenic album,  Hyoscyamus, Lobelia, Rauwolfia.
Autonomic dysfunctions	Aconitum nap, Nux vomica.
Enuresis nocturnal	Ephedra, Physostigma, Verbascum.
Retinitis, Optic neuritis	Alfalfa, Calotropis, Arsenic, Kali iodatum.
Hypothyroidism	Sinapis nigra.
Weak bone marrow	Allium sativa, Lobelia, Piper nigrim, Taraxacum.
Weak reproductive cells	Aconitum, Aloe socotrina, China, Lobelia, Lycopodium, Piper nigrim, Secale cor,   Sinapis, nigra, Veratrum album,  Viscum album, Zingiber.

Supporting measures

Promote periodic regular medical checkup. It will help to reduce the risk of complications.

Correct the severe mechanical conditions surgically.

Provide appropriate education and training.

Speech therapy.

Provide individual interactive measures and motivation to improve language proficiency. Provide necessary supporting items like hearing aids and glasses. 

Provide facilities for children watching cartoon films, storytelling, drawing etc.

Treat ear and chest infections properly.

Physical therapy. Make gentle massage on head, spinal column and limbs with oil to improve muscle tone. Essential oil like Lavender, Peppermint, Salvia and Jasmine are helpful to modify behavior changes.

Provide proper training about stretching exercises, rolling exercise, orofacial exercise and breath holding exercise. Promote breathing exercise only through one nose also.

Provide calcium rich food to prevent complication like adenoid and leukemia.

Provide sufficient food items containing vitamin A, B3, B6, E; omega 3 fatty acids, Zinc and Selenium.

Prefer organic rice, wheat, fruits and vegetables in diet.

Include vegetable items up to 65 % in diet.

Give adequate support to care givers.

Other favorable items  

Green tea, Black tea, Banana, Fragrances.

Alfalfa honey.

Eucalyptus honey.

Nux vomica honey.

Gelsemium honey.

Other unfavorable items  

Gluten, soybean, refined sugar and casein rich diet.

High caloric diet in obese children.

Spices.

World Down syndrome day is celebrated on 21 March every year.

Azadirachta indica. Kader Kochi.

Synonyms

Arishta, Azad, Neem, Arya veppu, Margosa tree, Sarva roga nivarini.

Constituents

Evergreen tree. Height 20 meters. Bark, seeds and leaves. Plant contains proteins, carbohydrates, sulphur, polyphenolics, gallic acid, coumarin, tannins, anti-oxidants, isoprenoids, limonoids, azadirone, azadiractin, and oil nimbin. 

Therapeutics

This is medicine for hyperacidity, anorexia, and disorders due to bile insufficiency.

It is medicine for night blindness, absent mindedness, and loss of memory.

It is medicine for brachialgia, shoulder fibrositis, polyarthritis, chikungunya, rheumatic pain, and intermittent fever.

It has anti-malarial, anti-viral, anthelmintic and anti-cancer properties (Viscum album).

It is medicine for diabetes.

It is medicine for old ulcer, and leprosy.

It is the antidote in insects bite, and viper poisoning (Milk).

It promotes circulation of fluids.

It is remedy for breast neoplasm.

It is remedy for male infertility.

Leaves have contraceptive properties.

Smoke of leaves was used as a mosquito and fly’s repellent.

Word “arishta” (Sanskrit) means wound healing plant.

Dose

2 to 10 drops.

Dilution.

Viscum album. Kader Kochi.

Synonyms

Mistletoe, Iscidor.

Constituents

Hemi parasitic plant. It found commonly in crown of broad -leaved trees.  Length of stem 1 meter. Fruits appear in Christmas season. Leaf, white berries, and stem contain lectin, viscumin (It is similar to abrin and ricin), oleanolic acid, and sulphur compounds.

Therapeutics

This is antiviral and anti-microbial medicine (Hepatitis C, HIV, influenza, chikungunya). 

It is medicine for epilepsy, and paralysis.

It is medicine for neuralgia, sciatica, and spinal pains of female.

It is medicine for anxiety, and tachycardia.

It is cardiac depressant (Cinchona, Veratrum viride).

It is anticoagulant medicine (Melilotus).

It is medicine for ventricular hypertrophy.

It is medicine for hyperglycaemia, and hypertriglyceridemia.

It is medicine for polyarthritis.

It is medicine for difficult labour.

It is the remedy for petit mal epilepsy (Valariana, Thuja, Helleborus).

It is remedy for spasm, and chorea (Nux vomica).

It is remedy for cerebral ischemia, and hypotension.

It is remedy for sun stroke, and radiation sickness (Muscle pain and fatigue).

It is remedy for pain and weakness in influenza (Ricinus communis, Gelsemium).

It is remedy cardiac failure (Digitalis).

It is remedy for arteriosclerosis.

It is remedy for degeneration of pancreas, and hypoglycaemia.

It is remedy for melanoma, cancer of breast, and cancer in bladder (Thuja, Ricinus communis, Arsenic album).

It is remedy for chronic hepatitis.

It is remedy for chronic ulcer. It improves micro circulation (Arsenic album).

It is the remedy for barrenness, and infertility (Azadirecta, Nux vomica, Thuja).

It is remedy for dysmenorrhoea.

It is remedy for chorea, and muscle spasm due to uterine congestion and amenorrhea.

It is remedy for reflex epilepsy, and hysteria from uterine stimulation.

It is remedy for haemolytic anaemia.

It is remedy for lowered cerebral circulation (Secale cor, Aconitum, Veratrum album, Arsenic album, Valerian, Ustilago).

It is remedy for autoimmune diseases.

It had been used as arrow poison, and anti-evil drug. It had been kept in house as token for fortune (Helleborus, Sinapis).  

It was Druid's medicine (Aloe, Lycopodium, Verbena). They collected this medicine on the sixth night of the winter solstice, wearing white clothes and using gold sickles.

It is the antidote in spider toxin, ergot poison, snake poison, castor bean toxin, and arsenic album (Veratrum album).

It had been used to make Christmas tree.

It had been considered a panacea (Thuja, Ginseng, Aconitum, Helleborus, Althea officinalis, Camphor, Terminalia chebula, Tinospora cordifolia, Justicia adhatoda, Mercurius, Sulphur, Nigella sativa).

Dose

1 to 6 drops. 
Dilution.